Progressive nodular histiocytosis

  • Adult onset
  • Superficial and deep yellow-brown papules, sparing flexors, leonine facies
  • No mucosal or visceral involvement
  • Pathology
    • Superficial lesions have foamy macrophages
    • Deep lesions have spindled histiocytes
  • Lesions progress, recalcitrant to surgical and medical therapy