Infeções Fúngicas Sistémicas

True pathogens

Clinical patterns of systemic mycoses from true pathogens

Asymptomatic primary infection

Healed primary infections

Acute and chronic pulmonary and disseminated infections (different sites of predilection eg lymph nodes)

Primary cutaneous infections (rare)

Relation to HIV and biologics

North American Blastomycosis

Coccidioidomycosis

South American Blastomycosis / Paracoccidiodomycosis

Opportunistic pathogens

Clinical patterns

Usually in the setting of onychomychosis with paronychia that evolves

At the sites of dressings, previous IV access

Purpuric or necrotic look (eschar)

Systemic opportunistic infection with disseminated cutaneous disease

Patients with stem cell transplant and hematologic malignancies are at highest risk

Early tissue biopsy and culture is critical

Disseminated Candidiasis

Mucor or Zygomycosis

Phaeohyphomycosis
Hyalohyphomycosis

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Opportunistic

Disseminated Candidiasis

Mucor or Zygomycosis

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