Atopic Eruption of Pregnancy | Prurigo Gestationis

AKA
  • Prurigo of pregnancy
  • Besnier’s “prurigo gestationis”
  • Nurse’s “early-onset prurigo” of pregnancy
  • Spangler’s “papular dermatitis of pregnancy”
  • Pruritic folliculitis of pregnancy
 
Onset timeline in the pregnancy
  • Occur EARLY during pregnancy
 
Clinical presentation
  • Pruritic papules and eczematous plaques
  • 3 fenómenos
    • Tipo E (lesões Eczematiformes)
    • Tipo P (lesões tipo Prurigo like)
    • Foliculite pruriginosa da gravidez (raro)
      • Pápulas e pústulas foliculoentradas, mais no abdómen
 
Mechanism
  • Predominance of Th2 immune response during pregnancy
    • Atopic predisposition
    • Not considered a flare-up of pre-existent atopic dermatitis
 
Risk of recurrence with future pregnancies
  • Likely to recur
 
Mother and fetal complications
  • No maternal or fetal risk
 
Treatment
  • Resolução 2 semanas após o parto
  • Topical corticosteroids
  • Systemic anti-histamines
  • UVB em doença grave
  • Dupilumab (dados escassos)