Drug induced hyperpigmentation or discoloration

  • Numerous drugs have been implicated in the development of blue-gray pigmentation of the skin and associated with corneal and sclera opacities
  • Most of them are related to the use of drugs of the phenothiazine family
    • Chrorpromazine
    • Fluphenazine
  • Tricyclic antiepressants
    • Imipramine